Morphology, secretion, and transplantability of ten mouse ovarian neoplasms induced by intrasplenic ovarian grafting.

Ovaries grafted into the spleens of gonadecto mized hosts are transformed into neoplasms in rats (2,14), mice (4, 7, 9, 11, 12), and rabbits (15). Al though there is a rapidly growing literature on the production of such ovarian neoplasms, very few reports have been concerned with their transplantability. Li and Gardner (11) stated that they made successful primary subpassages of several neoplasms obtained from intrasplenic ovarian grafts in mice but did not elaborate the details. Furth (4) transplanted fragments from eighteen different intrasplenic grafts, and only two were successfully passed. Furth's primary subpassages